The Centers for Disease Control and Prevention (CDC) is warning of a new Escherichia coli (E. coli) O157:H7 outbreak.

The CDC said 37 people in four states are known to have been infected in the outbreak. Of those, 15 are in Michigan.

Several sick people ate sandwiches with romaine lettuce at Wendy's restaurant, the agency said.

Wendy’s has removed romaine used in sandwiches from locations in the region.

E. coli disease frequently incorporates extreme stomach issues, looseness of the bowels, and regurgitating.

The CDC said people usually recover in five to seven days, although some infections can be life-threatening.

The CDC has yet to confirm the actual source of the outbreak.

This is the first E. coli outbreak to be included in the CDC's list of E. coli outbreaks for 2022.